Y.: Journal of Neuropathology and Experimental Neurology, 62, 644 (2003).īiotin conjugated Phosphorylated α-Synuclein, Monoclonal AntibodyĪnti Phosphorylated α-Synuclein, Monoclonal Antibody (pSyn#64), Biotin-conjugatedĬourtesy of Kuwabara and Iwatsubo, Graduate School of Medicine, The University of Tokyo This antibody is available for research in the Lewy body-related pathology.ġ) Fujiwara. This antibody does not react with normal α-synuclein, but recognizes only accumulated phosphorylated α-synuclein. Lewy body, a substance specifically found in nerve cells affected with Parkinson’s disease or dementia with Lewy body (DLB), contains α-synuclein protein of which serine at 129th position is specifically phosphorylated. Phosphorylated α-Synuclein, Monoclonal AntibodyĪnti Phosphorylated α-Synuclein, Monoclonal Antibody (pSyn#64)īrain section of dementia with Lewy bodiesĬourtesy of Iwatsubo,T., Graduate School of Medicine, The University of TokyoĪmino acid residue 124-134 of human α-synuclein with phosphorylated serine at position 129
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